bax channel blocker (Tocris)

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Tocris bax channel blocker
Bax Channel Blocker, supplied by Tocris, used in various techniques. Bioz Stars score: 93/100, based on 11 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/bax+channel+blocker+2160/Bax+channel+blocker/pmc13019251-161-14-27
Average 93 stars, based on 11 article reviews

bax channel blocker - by Bioz Stars, 2026-10

93/100 stars

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Mouse Assay:

Article Title: Sub-lethal apoptotic stress enables mtDNA release during senescence and drives the SASP
Article Snippet: .. Mice were injected intraperitoneally with 10 mg/kg of Bax Channel Blocker (BCB; Tocris Bioscience, 2160) three times a week for three months, at which point animals were euthanized and tissues were collected for analysis. ..

Injection:

other:

Article Title: Development of novel cytoprotective small compounds inhibiting mitochondria-dependent cell death
Article Snippet: Bax Channle Blocker , Tocris , No. 2160.

Article Title: Modulation of axon degeneration
Article Snippet: Cat. No. 440202) (CAS: 154447-36-6) Cdk5 Seliciclib (R- roscovitine/CYC202) (CAS: 186692-46-6) Adenylyl cyclase Forskolin (Calbiochem Cat. No. 344270) (CAS: 66575-29-9) NKH 477 (Tocris Cat. No. 1603) (CAS: 138605-00-2) Transcription Actinomycin D (Calbiochem Cat. No. 114666) (CAS: 50-76-0) JNK SP600125 (Calbiochem Cat. No. 420119) (CAS: 129-56-6) JNKV Inhibitor AS601245 (Calbiochem Cat. No. 420129 JNKVIII Inhibitor Calbiochem Cat. No. 420135 Bax Channel Bax Channel Blocker (Tocris Cat. No. 2160) (CAS: 335165-68-9) Ih Channel ZD7288 (Tocris Cat. No. 1000) (CAS: 133059-99-1) CAMK STO-609 (Calbiochem Cat. No. 570250) (CAS: 52029-86-4) Protein Synthesis Anisomycin (CAS: 22862-76-6) Cycloheximide (CAS: 66-81-9) TABLE 3 Target Compounds Structure CAS/Reference Proteasome Bortezomib [(1R)-3-methyl-1-({(2S)-3- CAS: 179324- (Velcade TM) phenyl-2-[(pyrazin-2- 69-7 ylcarbonyl)amino]propanoyl} Adams et al., amino)butyl]boronic acid Cancer Invest.

Recombinant:

Article Title: Fluoxetine Acts as a Calcium-Dependent Sensitizer of TRAIL-Induced Apoptosis in Glioblastoma Multiforme
Article Snippet: Dimethyl sulfoxide (DMSO), bovine serum albumin (BSA, cat. A7906), fluoxetine hydrochloride (FLX, cat. 56296-78-7), and 1-Naphthylacetyl spermine trihydrochloride (NASPM, cat. N193) were purchased from Millipore Sigma (Burlington, MA, USA). .. Recombinant human TRAIL (cat. 310-04) was purchased from PeproTech (Rocky Hill, NJ, USA), and Bax channel blocker (BCB, cat. 2160) and calpeptin (cat. 0448) were purchased from Tocris (Bristol, UK). .. Pluronic F-127, Fluo-4, AM (cat. F14201 ), and Fura-Red, AM (cat. F3021) were purchased from Thermo Fisher Scientific (Waltham, MA, USA).

Infection:

Article Title: Caspr1 is a host receptor for meningitis-causing Escherichia coli
Article Snippet: .. When indicated, the neurons were pretreated with apoptosis inhibitors including Bax channel blocker (10 μM, Tocris), mitochondrial inhibitor iMAC2 (10 μM, Tocris), pan Caspase inhibitor Z-VAD-FMK (10 μM, Tocris) and Caspase3 inhibitor Z-DEVD-FMK (10 μM, Tocris), respectively, for 30 min before bacterial infection. ..

Article Title: Caspr1 is a host receptor for meningitis-causing Escherichia coli
Article Snippet: .. Reply: According to reviewer’s suggestion, the detained information of the inhibitors used in Fig. S7D were provided in the figure legend of Fig. S7D as follows” When indicated, the neurons were pretreated with apoptosis inhibitors including Bax channel blocker (10 μM, Tocris), mitochondrial inhibitor iMAC2 (10 μM, Tocris), pan Caspase inhibitor Z-VAD-FMK (10 μM, Tocris) and Caspase3 inhibitor Z-DEVD-FMK (10 μM, Tocris), respectively, for 30 min before bacterial infection”. ..

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